Vijay G Sankaran Selected Research

Fetal Hemoglobin (Hemoglobin F)

1/2023	Fetal Hemoglobin Regulation in Beta-Thalassemia.
1/2023	Massively parallel base editing to map variant effects in human hematopoiesis.
10/2021	Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing.
1/2020	Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation.
1/2019	Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.
1/2016	Regulation of the fetal hemoglobin silencing factor BCL11A.
3/2013	Clinical experience with fetal hemoglobin induction therapy in patients with β-thalassemia.
1/2013	The switch from fetal to adult hemoglobin.
2/2012	Persistence of fetal hemoglobin expression in an older child with trisomy 13.
1/2012	Fetal hemoglobin levels and morbidity in untransfused patients with β-thalassemia intermedia.

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Vijay G Sankaran Research Topics

Disease

17	Sickle Cell Anemia (Hemoglobin S Disease) 03/2023 - 02/2008
14	Thalassemia 03/2023 - 12/2010
12	Anemia 01/2023 - 05/2011
7	beta-Thalassemia (Cooley's Anemia) 01/2023 - 02/2008
6	Neoplasms (Cancer) 10/2023 - 05/2011
5	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2021 - 07/2012
2	Bone Marrow Failure Disorders 01/2023 - 01/2023
2	Leukemia 01/2023 - 12/2019
2	Disease Progression 12/2021 - 11/2013
2	Aplastic Anemia (Anemia, Hypoplastic) 01/2021 - 07/2012
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2021 - 12/2010
2	Mitochondrial Diseases (Mitochondrial Disease) 10/2020 - 05/2016
2	Chronic Renal Insufficiency 01/2020 - 01/2018
2	Trisomy 13 Syndrome 02/2012 - 01/2011
1	alpha-Thalassemia 01/2023
1	Congenital Bone Marrow Failure Syndromes 01/2023
1	Multiple Sclerosis 01/2023
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2023
1	Multiple Myeloma 10/2022
1	Myeloid Leukemia (Leukemia, Myelocytic) 01/2022
1	Down Syndrome (Down's Syndrome) 01/2022
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 12/2021
1	Neutropenia 01/2021
1	Brain Diseases (Brain Disorder) 01/2021
1	Intellectual Disability (Idiocy) 01/2021
1	Craniofacial Abnormalities 01/2021
1	Atrophy 01/2021
1	Sepsis (Septicemia) 12/2020
1	Primary Myelofibrosis (Myelosclerosis) 01/2020
1	Infections 12/2019
1	Thrombocytopenia (Thrombopenia) 01/2019
1	Iron Deficiencies 01/2019
1	Sickle Cell Trait 01/2018
1	Stroke (Strokes) 01/2018
1	Porphyrias (Porphyria) 10/2016
1	Hereditary Elliptocytosis 07/2016
1	Inflammation (Inflammations) 01/2016
1	T-Cell Leukemia (Leukemia, T Cell) 07/2014
1	Hemoglobinopathies 09/2011
1	Trisomy (Trisomies) 01/2011
1	Retinoblastoma (Glioblastoma, Retinal) 09/2008
1	Pain (Aches) 08/2008

Drug/Important Bio-Agent (IBA)

20	Fetal Hemoglobin (Hemoglobin F)IBA 01/2023 - 02/2008
8	Hemoglobins (Hemoglobin)IBA 06/2015 - 02/2008
7	GlobinsIBA 01/2023 - 02/2008
6	Ribosomal Proteins (Ribosomal Protein)IBA 01/2021 - 07/2012
3	Proteins (Proteins, Gene)FDA Link 01/2023 - 05/2016
3	Mitochondrial DNA (mtDNA)IBA 12/2021 - 12/2019
3	Erythropoietin FDA Link 01/2021 - 05/2011
2	ChromatinIBA 10/2022 - 12/2021
2	gamma-GlobinsIBA 08/2010 - 08/2008
1	RNA (Ribonucleic Acid)IBA 10/2023
1	Histones (Histone)IBA 01/2023
1	vedolizumabIBA 01/2023
1	Transcription Factors (Transcription Factor)IBA 01/2023
1	Daclizumab (Zenapax)FDA Link 01/2023
1	Deubiquitinating EnzymesIBA 01/2023
1	GATA1 Transcription FactorIBA 01/2022
1	Protein Isoforms (Isoforms)IBA 01/2022
1	Genetic Markers (Genetic Marker)IBA 12/2021
1	TransposasesIBA 12/2021
1	SteroidsIBA 01/2021
1	UridineIBA 01/2021
1	IntegrinsIBA 12/2020
1	Protein Subunits (Protein Subunit)IBA 10/2020
1	Calmodulin (Calcium-Dependent Activator Protein)IBA 10/2020
1	roxadustatIBA 01/2020
1	IronIBA 01/2020
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 01/2020
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2019
1	RNA Splice SitesIBA 01/2019
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2019
1	NucleotidesIBA 01/2019
1	CytokinesIBA 01/2017
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 10/2016
1	PorphyrinsIBA 10/2016
1	Heme (Haem)IBA 10/2016
1	Adenosine Triphosphate (ATP)IBA 10/2016
1	EnzymesIBA 10/2016
1	LAN antigenIBA 10/2016
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 05/2016
1	Mitochondrial Processing PeptidaseIBA 05/2016
1	Oxygen (Dioxygen)IBA 01/2016
1	Biomarkers (Surrogate Marker)IBA 11/2013
1	MicroRNAs (MicroRNA)IBA 01/2011
1	Peptides (Polypeptides)IBA 12/2010
1	A-factor (Streptomyces)IBA 08/2010
1	Retinoblastoma ProteinIBA 09/2008
1	DNA (Deoxyribonucleic Acid)IBA 08/2008
1	beta-Globins (beta Globin)IBA 08/2008

Therapy/Procedure

10	Therapeutics 03/2023 - 01/2012
1	Immunotherapy 01/2023
1	Transjugular Intrahepatic Portasystemic Shunt 01/2023
1	Transplantation 01/2023
1	Stem Cell Transplantation 01/2022
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 12/2020
1	Hematopoietic Stem Cell Transplantation 12/2016